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Chemistry of Bioactive Natural Compounds

The research consists in the extraction, isolation and characterization of organic natural compounds possessing biological activities from plants and bacteria.

Activity start  
Publications - 2013 - Articolo in rivista
Behzad Zolfaghari, Masoud Sadeghi, Raffaele Troiano, Virginia Lanzotti (2013). Vavilosides A1/A2–B1/B2, new furostane glycosides from the bulbs of Allium vavilovii with cytotoxic activity. BIOORGANIC & MEDICINAL
CHEMISTRY, vol. 21, p. 1905-1910, ISSN: 0968-0896
- 2013 - Articolo in rivista
Masoud Sadeghi, Behzad Zolfaghari, Mauro Senatore, Virginia Lanzotti (2013). Spirostane, furostane and cholestane saponins from Persian leek with antifungal activity. FOOD CHEMISTRY, vol. 141 , p. 1512-1521, ISSN: 0308-8146
- 2013 - Articolo in rivista
Virginia Lanzotti, Giuliano Bonanomi, Felice Scala (2013). What makes Allium species effective against pathogenic microbes?. PHYTOCHEMISTRY REVIEWS, p. 1-22, ISSN: 1568-7767, doi: 10.1007/s11101-013-9295-3
- 2012 - Articolo in rivista
V. Lanzotti, A. Romano, G. Bonanomi, S. Lanzuise, F. Scala (2012). Antifungal saponins from bulbs of white onion, Allium cepa L.. PHYTOCHEMISTRY, vol. 74, p. 133-139, ISSN: 0031-9422
- 2011 - Articolo in rivista
A. Romano, D. Vitullo, A. Di Pietro, G. Lima, V. Lanzotti (2011). Antifungal Lipopeptides from Bacillus amyloliquefaciens Strain BO7. Journal of Natural Products, 74, 145-151. JOURNAL OF NATURAL
PRODUCTS, vol. 74, p. 145-151, ISSN: 0163-3864
- 2009 - Articolo in rivista
COREA G, DI PIETRO A, FATTORUSSO E, LANZOTTI V (2009). Jatrophane Diterpenes as Inhibitor of Multidrug Resistance. PHYTOCHEMISTRY REVIEWS, vol. 8, p. 431-447, ISSN: 1568-7767
- 2008 - Articolo in rivista
E. Barile, M. Borriello, A. D. Pietro, A. Doreau, C. Fattorusso, E. Fattorusso, V. Lanzotti (2008). Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 6, p. 1756-1762, ISSN: 1477-0520, doi: 10.1039/b800485d
- 2007 - Articolo in rivista
E. Barile, G. Bonanomi, V. Antignani, B. Zolfaghari, S. E. Sajjadi, F. Scala, V. Lanzotti (2007). Saponins from Allium minutiflorum with antifungal activity. PHYTOCHEMISTRY, vol. 68, p. 596-603, ISSN: 0031-9422, doi: 10.1016/j.phytochem.2006.10.009
- 2005 - Articolo in rivista
G. Corea, E. Fattorusso, V. Lanzotti, P. D. Meglio, P. Maffia, G. Grassia, A. Ialenti, A. Ianaro (2005). Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as Antiinflammatory agent. JOURNAL OF MEDICINAL CHEMISTRY, vol. 48, p. 7055-7062, ISSN: 0022-2623, doi: 10.1021/jm050321r
- 2005 - Articolo in rivista
G. Corea, E. Fattorusso, V. Lanzotti, R. Capasso, A. A. Izzo (2005). Antispasmodic saponins from bulbs of red onion, Allium cepa L. var. Tropea. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 53, p. 935-940, ISSN: 0021-8561, doi: 10.1021/jf048404o
Permanent staff Virginia Lanzotti (CHIM/06) (Professore Associato) UNINA, Felice Scala (professore ordinario UNINA), Giuliano Bonanomi (ricercatore) UNINA
Temporary or external staff Bruna De Falco (dottoranda di ricerca) UNINA, Giuseppe Lima (professore associato) UNIMOL, Elisa Barile (ricercatore) Barnham Institute, San Diego, USA, Paolo Curir (ricercatore) CRA, Sanremo, Attilio Di Pietro (ricercatore) CNRS, Lyone, Francia, Behzad Zofaghari (associate professor), Isfahan, IRAN, Masoud Sadeghi (assistant professor), Isfahan, IRAN
Collaborations  
SSD  
Projects - MIUR (IT08F0A8E8) “Molecular signalling between biocontrol agents and fungal pathogens in the rhizosphere of agronomically important crops”, Responsabile Gruppo Chimico
- MIUR (20089LSZ2A_003) “Studies on biocontrol agents and their biomolecules to optimize the suppressive activity of natural amendments against soilborne pathogens of horticultural crops” , Responsabile Gruppo Chimico
Recognitions and awards - Premio Pierre Fabre Award 2003 della Phytochemical Society of Europe con la motivazione "Excellence in Phytochemsitry". L'annuncio del premio e il curriculum della Lanzotti sono stati pubblicati su Phytochemistry, anno 2004, vol. 65, pp. 2417-2418.
- Relazione plenaria su Invito: V. Lanzotti (2005) Jatrophane Diterpenes as Inhibitors of Multidrug Resistance. XXI Conference on Isoprenoids, Bialowieza, Poland.
Scientific events - 2014 – Curatela – Editor of Issue
Lanzotti V (a cura di) (2014). Natural Products in Cancer Prevention and Therapy. Anticancer Agents in Medicinal Chemistry, issue 09 (September 2014), Bentham, ISSN: 1875-5992
- 2014 – Curatela – Editor of Issue
Lanzotti V (a cura di) (2014). Natural Products in Cancer Prevention and Therapy. Di Fundamentals and perspectives of natural products research (PSE meeting Naples 25-28 June 2013). PHYTOCHEMISTRY REVIEWS, vol. 13, issue 3 (15 September 2014), Dordrecht:Springer, ISSN: 1568-7767
- 2013 – Chairman of Congress
Natural Compounds in Cancer Prevention and Therapy, Phytochemical Society of Europe, 2nd Edition, Naples 25-28 June 2013
- 2009 – Curatela – Editor of Book
OSBOURN AE, LANZOTTI V (a cura di) (2009). Plant-derived Natural Products: Synthesis, Function and Application. vol. XIV, p. 1-598, Springer, ISBN: 9780387854977
- 2009 – Curatela – Editor of Issue
Lanzotti V (a cura di) (2009). Natural Products in Cancer Therapy. Di Fundamentals and perspectives of natural products research (PSE meeting Naples 23-26 September 2008). PHYTOCHEMISTRY REVIEWS, vol. 8, p. 311-502, Dordrecht:Springer, ISSN: 1568-7767
- 2008 – Chairman of Congress
Natural Compounds in Cancer Prevention, Phytochemical Society of Europe, Naples 23-26 September 2008
Technology and know-how transfers  
Other