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Computational and molecular platform for analysis and idenfication of R genes

Computational-and-molecular-platform-for-analysis-and-idenfication-of-R-genes A dedicated repository of the R-gene family, specific prediction tools  and a molecular platform are developed to discover new resistance genes for diagnostic purposes and to elucidate mechanisms of interaction between plants and pathogens.

Activity start 2002
Publications - Andolfo G, Sanseverino W, Rombauts S, Van der Peer J, Bradeen J.M., Carputo D, Frusciante L, Ercolano M.R. 2013. Overview of tomato (Solanum lycopersicum) candidate pathogen recognition genes reveals important Solanum R locus dynamics . New Phytologist, ISSN: 0028-646X, doi: 10.1111/j.1469-8137.2012.04380.x. (Q1)
- Sanseverino W, Frusciante L, Ercolano MR. 2013. PRGdb 2.0: towards a community-based database model for the analysis of R-genes in plants. Nucleic Acids Research. 41D1 D1167 D1171 10.1093/nar/gks118.  (Q1)
- Ercolano MR, Sanseverino W, Carli P, Ferriello F, Frusciante L. 2012. Genetic and genomic approaches for R-gene mediated disease resistance in tomato: retrospects and prospects. Plant Cell Reports, 31: 973-985, ISSN: 0721-7714, doi: 10.1007/s00299-012-1234-z. (Q1)
- Faino L, Azizinia S,  Hassanzadeh BH,  Verzaux E,  Ercolano MR, R. G. F., Bai YL. 2012. Fine mapping of two major QTLs conferring resistance to powdery mildew in tomato. Euphytica, 184:223-234, ISSN: 0014-2336, doi: 10.1007/s10681 (Q1)
- Formisano G, Roig, C, Esteras C, Ercolano MR, Nuez F, Monforte AJ, Picò MB. 2012. Genetic diversity of Spanish Cucurbita pepo landraces: An unexploited resource for summer squash breeding. Genetic Resources and Crop Evolution  59(6):1169-1184 doi:10.1007/s10722-011-9753-y (Q1)
- Formisano G, Paris HS, Frusciante L, Ercolano MR. 2010. Commercial Cucurbita pepo squash hybrids carrying disease resistance introgressed from Cucurbita moschata have high genetic similarity. Plant Genetic Resources: Characterisation and Utilisation  8(3):198 - 203  doi: 10.1017/S1479262110000183 (Q2)
- Ballvora A, Ercolano MR, Weiß J, Mekse K, Bormann CA, Oberhagemann P, Salamini F & Gebhardt C. 2002. The R1 Gene for Potato Resistance to Late Blight (Phytophthora infestans) Belongs to the Leucine Zipper/NBS/LRR Class of Plant Resistance Genes. Plant Journal 30(3):351-361 (Q1)
- Sanseverino W, Roma G, De Simone M, Faino L, Melito S, Stupka E, Frusciante L, Ercolano MR. 2010. PRGdb: a bioinformatics platform for plant resistance gene analysis. Nucleic Acids Research, p. 1-8, ISSN: 0305-1048, doi: 10.1093/nar/gkp978.  (Q1)
- Sanseverino W, Ercolano MR. 2012. In silico approach to predict candidate R proteins and to define their domain architecture. BMC Research. Notes  5  doi: 10.1186/1756-0500-5-678. (Q2)
Permanent staff Maria Raffaella Ercolano (AGR/07); Luigi Frusciante (AGR/07)
Temporary or external staff Andolfo Giuseppe (PhD student, UNINA), Claudio Capuozzo (PhD student at the Semiorto Sementi Company), Harris Paris (Dept. of Vegetable Crops, Agricultural Research Organization, Ramat Yishay , Israel), Yuling Bay (Laboratory of Plant Breeding of Wageningen University in the Netherlands), Christine Gebhard (Max-Planck-Institut in Cologne, Germany), Van der Peer J (Gent University, Belgium), Hermoso A. (Bioinformatics Core Facility CRG Barcellon, Spain),  Jonathan Jones (Sainsbury Laboratory, Norwich, UK)
Collaborations INTERNAZIONALI:  Rombauts S,  Van der Peer J (Gent Univeristy (Belgium); James M. Bradeen (University of Minnesota, USA); Sanseverino W (Sequentia, Barcellona); Hermoso A.  (Bioinformatics Core Facility CRG Barcellon, Spain),  Jonathan Jones (Sainsbury Laboratory, Norwich, UK); Roma G (CRG- Barcellona; Faino L (University of Wageningen,NL). NAZIONALI: Melito S (UNISS), Stupka E (San Raffaele di Milano)
SSD AGR07
Projects - Potenziamento della filiera pomodoro attraverso applicazioni integrate di post-genomica GenoPOM-pro (PON MiUR. 01/07/2012-30/06/2015, partecipante)
- Valorizzazione di produzioni ortive campane di eccellenza con strumenti di genomica avanzata GenHORT ( PON MiUR. 01/07/2012-30/06/2015, partecipante)
Recognitions and awards  
Scientific events  
Technology and know-how transfers Sviluppo Database PRGdb
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